Willem Dafoe plays John La Tour, a drugs delivery man working for Ann, an up-market dealer (Susan Sarandon). An ex-junkie now in his mid-forties and suffering from insomnia, John begins to see the importance of changing his life and making a fresh start. At the same time, he begins to recognise his feelings for Ann, while she sees a foray into the cosmetics business as her way out of her old lifestyle. However, it is not an easy path.
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