Spoiler
the film eventually begins to explore some significant questions around medical research ethics, mental health, and the fundamental forces that shape us as human beings - with that last element especially taking on an emotional weight in the context of what we discover about the brothers and how their separation impacted them both in and of itself (in a haunting echo of current events regarding the separation of children from their families) and in terms of the familial dynamics they were placed into as a result.
Wardle also raises worthwhile questions about the ultimate value of ethically unsound but perhaps scientifically valid research; is it a waste to neglect the knowledge that could be gained from such studies solely due to the harm it may have caused its subjects, or does that damage inherently stain whatever results one may be tempted to glean from the data? The interviews and portraits of some of the scientists involved are alternately stimulating in their intellectual probing of these issues and subtly horrifying in their clinical detachment to the consequences of their work; one can't help but recoil from the juxtaposition of assertions about the potentially historic importance of the central study with the descriptions of its consequences on entirely innocent children.
As effectively as the film raises these difficult questions, its key flaw is that it tries too hard to lead the audience to definitive answers that are neither entirely earned or necessary; better to force the audience to interrogate and debate these ideas more deeply than leave the theater feeling a false sense of resolution and clarity where there is less of either than the film might have one believe.
Wardle also raises worthwhile questions about the ultimate value of ethically unsound but perhaps scientifically valid research; is it a waste to neglect the knowledge that could be gained from such studies solely due to the harm it may have caused its subjects, or does that damage inherently stain whatever results one may be tempted to glean from the data? The interviews and portraits of some of the scientists involved are alternately stimulating in their intellectual probing of these issues and subtly horrifying in their clinical detachment to the consequences of their work; one can't help but recoil from the juxtaposition of assertions about the potentially historic importance of the central study with the descriptions of its consequences on entirely innocent children.
As effectively as the film raises these difficult questions, its key flaw is that it tries too hard to lead the audience to definitive answers that are neither entirely earned or necessary; better to force the audience to interrogate and debate these ideas more deeply than leave the theater feeling a false sense of resolution and clarity where there is less of either than the film might have one believe.